Journal of Oncology

Research Article

The Significant Influence of the Neuroendocrine Component on the Survival of Patients with Gastric Carcinoma Characterized by Coexisting Exocrine and Neuroendocrine Components

Table 3

Cox regression model for the NE component.


NE component	Number	Univariate analysis		Multivariate analysis
NE component	Number	HR (95% CI)	p value	HR (95% CI)	p value

No	190	1 (reference)		1 (reference)
Yes	95	1.534 (0.935, 2.518)	0.090	1.292 (0.771, 2.164)	0.330
No	190	1 (reference)		1 (reference)
GC with NED (0<NE<30)	32	1.358 (0.661, 2.791)	0.404	1.224 (0.588, 2.549)	0.590
MANEC (30≤NE≤70%)	29	1.209 (0.543, 2.695)	0.642	0.897 (0.392, 2.054)	0.797
NEC (70<NE<100)	34	2.318 (1.128, 4.766)	0.022	2.155 (1.011, 4.593)	0.047
No	190	1 (reference)
GC with NE component 0<NE≤10	30	1.429 (0.696, 2.938)	0.331
GC with NE component 10<NE<100	65	1.601 (0.0899, 2.849)	0.110
No	190	1 (reference)
GC with NE component 0<NE≤20	32	1.358 (0.661, 2.791)	0.405
GC with NE component 20<NE<100	63	1.656 (0.930, 2.946)	0.086
No	190	1 (reference)		1 (reference)
GC with NE component 0<NE≤30	42	1.131 (0.568, 2.256)	0.726	1.067 (0.530, 2.151)	0.855
GC with NE component 30<NE<100	53	2.013 (1.116, 3.633)	0.020	1.524 (0.816, 2.847)	0.186
No	190	1 (reference)		1 (reference)
GC with NE component 0<NE≤40	52	1.311 (0.716, 2.402)	0.380	1.172 (0.634, 2.167)	0.614
	52	1.311 (0.716, 2.402)	0.380	1.172 (0.634, 2.167)	0.614
GC with NE component 40<NE<100	43	1.959 (1.008, 3.806)	0.047	1.513 (0.749, 3.059)	0.249
No	190	1 (reference)
GC with NE component 0<NE≤50	54	1.379 (0.764, 2.487)	0.286
GC with NE component 50<NE<100	41	1.847 (0.927, 3.683)	0.081
No	190	1 (reference)
GC with NE component 0<NE≤60	58	1.169 (0.769, 2.435)	0.286
GC with NE component 60<NE<100	37	1.955 (0.951, 4.018)	0.068
No	190	1 (reference)		1 (reference)
GC with NE component 0<NE≤70	61	1.289 (0.725, 2.294)	0.388	1.060 (0.585, 1.920)	0.848
GC with NE component 70<NE<100	34	2.318 (1.128, 4.765)	0.022	2.156 (1.011, 4.597)	0.047
No	190	1 (reference)
GC with NE component 0<NE≤80	65	1.368 (0.778, 2.404)	0.276
GC with NE component 80<NE<100	30	2.070 (0.971, 4.412)	0.059
No	190	1 (reference)		1 (reference)
GC with NE component 0<NE≤90	67	1.334 (0.759, 2.344)	0.317	1.061 (0.592, 1.902)	0.842
GC with NE component 90<NE<100	28	2.253 (1.057, 4.802)	0.035	2.476 (1.088, 5.634)	0.031