A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer

Figure 3

Increased epithelial cell CTSS expression is associated with improved outcome in TNBC. Kaplan-Meier curves stratifying overall survival (OS) of (a) the BR300 TNBC patients-alone, (b) the bespoke TNBC enriched cohort-alone, and (c) the combined BR300 and bespoke TNBC cohorts, based on high or low CTSS expression in the (i) epithelial and (ii) stromal compartment. Log-Rank p-value and hazard ratio (HR) with 95% confidence intervals indicated. N=number of patients.

(a)

(b)

(c)