ANXA2 Silencing Inhibits Proliferation, Invasion, and Migration in Gastric Cancer Cells

Figure 3

(a) By KEGG pathway enrichment analysis, ANXA2 upregulated filopodia pathway, resulting in cell metastasis. Microfilament is one component of cytoskeleton; it is mainly composed of actin. ANXA2 upregulated regulation of actin cytoskeleton pathway and led to the rise of cell deformability. (b) By KEGG pathway enrichment analysis, ANXA2 upregulated focal adhesion pathway, resulting in cell motility, proliferation and survival.

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