Research Article

Colon Cancer Sidedness, Presentation, and Survival at Different Stages

Table 1

Patient’s demographic and clinical characteristics.

characteristicsSidedness (laterality)P-value
Right sided cancerLeft sided cancer
N = 85,779 (%)N = 78,201 (%)

Age
Mean (SD)68.5 ± 12.763.0 ± 13.0<0.001

Age group (years)
<506,798 (7.9)11,546 (14.8)<0.001
50-6935,523 (41.4)41,258 (52.8)
70-8943,458 (50.7)25,397 (32.5)

Gender
Male 40,389 (47.1)43,410 (55.5)<0.001
Female45,390 (52.9)34,791 (44.5)

Race
Hispanic8,579 (10.0)9,325 (11.9)<0.001
Black11,607 (13.5)9,182 (11.7)
White59,370 (69.2)50,391 (64.4)
Others6,223 (7.3)9,303 (11.9)

Insurance
Insured57,449 (67.0)49,801 (63.7)<0.001
Medicaid9,362 (10.9)10,553 (13.5)
insured/no specifics14,922 (17.4)12,677 (16.2)
uninsured2,470 (2.9)3,161 (4.0)
unknown1,576 (1.8)2,009 (2.6)

Marital status
Married44,909 (52.4)42,824 (54.8)<0.001
Divorced7,971 (9.3)7,483 (9.6)
Separated905 (1.1)1,048 (1.3)
Single12,187 (14.2)13,303 (17.0)
Unknown4,167 (4.9)4,385 (5.6)
Widowed15,640 (18.2)9,158 (11.7)

Geographic region
Northeastern13,587 (15.8)12,189 (15.6)<0.001
Midwestern8,801 (10.3)6,789 (8.7)
Western41,869 (48.8)40,144 (51.3)
Southern21,522 (25.1)19,079 (24.4)

Tumor Grade
Grade I6,560 (7.7)6,585 (8.4)
Grade II54,799 (63.4)54,616 (69.8)
Grade III16,540 (19.3)9,175 (11.7)<0.001
Grade IV2,713 (3.2)1,292 (1.7)
Unknown5,167 (6.0)6,533 (8.4)

AJCC (6th Edition stages)
I19,321 (22.5)20,240 (25.9)<0.001
II25,989 (30.3)18,744 (24.0)
III23,914 (27.9)22,391 (28.6)
IV16,555 (19.3)16,826 (21.5)

Histology
Mucinous adenocarcinoma9,172 (10.7)3,923 (5.0)
Adenocarcinoma NOS59,460 (69.3)57,095 (73.0)
Signet ring cell carcinoma 1,219 (1.4)523 (0.7)<0.001
Adenocarcinoma in adenomatous polyps 5,849 (6.8)8,117 (10.4)
Others (papillary, adenosquamous, medullary)10,079 (11.8)8,543 (10.9)
Treatment by surgery
Surgery performed79,083 (92.2)70,079 (89.6)<0.001
No surgery (other reasons)6,696 (7.8)8,122 (10.4)

T-staging<0.001
T014(0.02)44 (0.06)
T111,707 (13.7)16,304 (20.8)
T211,871 (13.8)9,311 (11.9)
T344,314 (51.7)36,608 (46.8)
T414,490 (16.9)12,069 (15.4)
Tx3,383 (3.9)3,865 (4.9)

N staging
N049,302 (57.5)44,227 (56.6)<0.001
N120,546 (24.0)20,155 (25.8)
N214,311 (16.7)11,865 (15.2)
Nx1,620 (1.9)1,954 (2.5)

SD = standard deviation, AJCC = American Joint Commission on Cancer, Nx = cancer in nearby lymph nodes cannot be measured, and <50 = 18-49.