Colon Cancer Sidedness, Presentation, and Survival at Different Stages

Table 2

Independent predictors of association between left versus right sided (reference) colon cancers.

Characteristics	Adjusted Risk Ratio (RR) 95% Confidence Interval	P-value
Male	1.14 (1.12-1.15)	<0.001
Race
Hispanic (ref)
Black	0.84 (0.82-0.86)	<0.001
White	0.95 (0.94-0.97)	<0.001
Others	1.16 (1.14-1.18)	<0.001
Age
<50 (ref)
50-69	0.84 (0.83-0.85)	<0.001
70-89	0.61 (0.60-0.62)	<0.001
Insurance
Insured (ref)
Medicaid	1.08 (1.07-1.10)	<0.001
Insured/no specifics	1.02 (1.01-1.04)	0.002
Uninsured	1.05 (1.03-1.08)	<0.001
Unknown	1.10 (1.07-1.13)	<0.001
Marital status
Married (ref)
Divorced	1.01 (0.99-1.03)	0.345
Separated	1.04 (1.00-1.09)	0.042
Single	1.02 (1.01-1.04)	0.002
Unknown	1.03 (1.01-1.05)	0.007
Widowed	0.97 (0.95-0.99)	0.001
Geographic region
Northeastern (ref)
Midwestern	0.93 (0.91-0.95)	<0.001
Western	0.96 (0.95-0.98)	<0.001
Southern	0.97 (0.95-0.98)	<0.001
AJCC6th_edition
Stage I (ref)
II	0.88 (0.87-0.90)	<0.001
III	1.01 (0.99-1.02)	0.460
IV	0.98 (0.96-1.00)	0.028
Tumor Grade
Grade I (Ref)
grade II	0.99 (0.97-1.01)	0.279
grade III	0.73 (0.71-0.75)	<0.001
grade IV	0.68 (0.65-0.71)	<0.001
Unknown	1.05 (1.02-1.07)	<0.001
Histology
Mucinous adenocarcinoma (ref)
Adenocarcinoma NOS	1.58 (1.54-1.62)	<0.001
Signet ring cell carcinoma	1.12 (1.04-1.21)	0.003
Adenocarcinoma in adenomatous polyps	1.75 (1.70-1.80)	<0.001
Others (papillary, adenosquamous, medullary)	1.42 (1.38-1.47)	<0.001
Treatment
No surgery (ref)
Surgery performed	0.92 (0.90-0.94)	<0.001

ref = reference; NOS = not otherwise specified.