Research Article
Colon Cancer Sidedness, Presentation, and Survival at Different Stages
Table 3
Independent predictors of overall survival (OS) for colon cancer.
| Characteristics | Adjusted HR (95% Confidence Interval) | P-value |
| Male | 1.18 (1.16-0.1.20) | <0.001 |
| Race | | | Hispanic (ref) | | Black | 1.15 (1.11-1.20) | <0.001 | White | 1.06 (1.02-1.09) | <0.001 | Others | 0.89 (0.85-0.92) | <0.001 |
| Age | | | <50 (ref) | | 50-69 | 1.26 (1.22-1.30) | <0.001 | 70-89 | 2.60 (2.47-2.64) | <0.001 |
| Insurance | | | Insured (ref) | | Medicaid | 1.39 (1.36-1.43) | <0.001 | Insured/no specifics | 1.14 (1.11-1.16) | <0.001 | Uninsured | 1.31 (1.25-1.37) | <0.001 | Unknown | 1.06 (1.00-1.13) | 0.062 |
| Marital status | | | Married (ref) | | Divorced | 1.21 (1.18-1.25) | <0.001 | Separated | 1.17 (1.08-1.26) | <0.001 | Single | 1.29 (1.26-1.32) | <0.001 | Unknown | 1.12 (1.07-1.17) | <0.001 | Widowed | 1.38 (1.35-1.42) | <0.001 |
| Geographic region | | | Northeastern (ref) | | Midwestern | 1.08 (1.05-1.12) | <0.001 | Western | 1.06 (1.03-1.08) | <0.001 | Southern | 1.14 (1.11-1.17) | <0.001 |
| AJCC6th edition | | | Stage I (ref) | | II | 1.30 (1.26-1.34) | <0.001 | III | 2.06 (2.00-2.12) | <0.001 | IV | 7.88 (7.63-8.13) | <0.001 |
| Tumor Grade | | | Grade I (Ref) | | grade II | 1.08 (1.04-1.12) | <0.001 | grade III | 1.47 (1.41-1.53) | <0.001 | grade IV | 1.58 (1.49-1.68) | <0.001 | Unknown | 1.18 (1.13-1.24) | <0.001 |
| Histology | | | Mucinous adenocarcinoma (ref) | | Adenocarcinoma NOS | 0.90 (0.87-0.92) | <0.001 | Signet ring cell carcinoma | 1.37 (1.28-1.47) | <0.001 | Adenocarcinoma in adenomatous polyps | 0.74 (0.71-0.78) | <0.001 | Others (papillary, adenosquamous, medullary) | 0.82 (0.79-0.86) | <0.001 |
| Treatment | | | No surgery (ref) | | Surgery performed | 0.39 (0.38-0.40) | <0.001 |
| Laterality | | | Right sided (ref) | | Left sided | 0.87 (0.85-0.88) | <0.001 |
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ref = reference; HR = hazard ratio. |