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Journal of Oncology
Volume 2019, Article ID 4359103, 11 pages
https://doi.org/10.1155/2019/4359103
Research Article

C-Reactive Protein to Prealbumin Ratio (CPR): A Novel Inflammatory-Nutritional Prognostic Factor for Predicting Cancer-Specific Survival (CSS) and Overall Survival (OS) in Patients with Resectable Esophageal Squamous Cell Carcinoma

1Department of Thoracic Oncological Surgery, Institute of Cancer Research and Basic Medical Sciences of Chinese Academy of Sciences, Cancer Hospital of University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, No.38 Guangji Road, Hangzhou 310022, China
2Key Laboratory Diagnosis and Treatment Technology on Thoracic Oncology, No. 38 Guangji Road, Zhejiang Province, Hangzhou 310022, China

Correspondence should be addressed to Ji-Feng Feng; moc.361@fijgnef and Xun Yang; moc.anis@jzgnaynux

Received 2 April 2019; Accepted 16 June 2019; Published 14 July 2019

Guest Editor: Philippe-Richard J. Domeyer

Copyright © 2019 Ji-Feng Feng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. L. Siegel, K. D. Miller, and A. Jemal, “Cancer statistics, 2015,” CA: A Cancer Journal for Clinicians, vol. 65, no. 1, pp. 5–29, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Ferlay, H. R. Shin, F. Bray, D. Forman, C. Mathers, and D. M. Parkin, “Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008,” International Journal of Cancer, vol. 127, no. 12, pp. 2893–2917, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. K. J. Napier, M. Scheerer, and S. Misra, “Esophageal cancer: A review of epidemiology, pathog enesis, staging workup and treatment modalities,” World Journal of Gastrointestinal Oncology, vol. 6, no. 5, pp. 112–120, 2014. View at Publisher · View at Google Scholar
  4. L. Bedenne, P. Michel, O. Bouché et al., “Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102,” Journal of Clinical Oncology, vol. 25, no. 10, pp. 1160–1168, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. M. J. D. Arnal, Á. F. Arenas, and Á. L. Arbeloa, “Esophageal cancer: risk factors, screening and endoscopic treatment in Western and Eastern countries,” World Journal of Gastroenterology, vol. 21, no. 26, pp. 7933–7943, 2015. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Mantovani, P. Allavena, A. Sica, and F. Balkwill, “Cancer-related inflammation,” Nature, vol. 454, no. 7203, pp. 436–444, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Szkandera, M. Stotz, G. Absenger et al., “Validation of C-reactive protein levels as a prognostic indicator for survival in a large cohort of pancreatic cancer patients,” British Journal of Cancer, vol. 110, no. 1, pp. 183–188, 2014. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Shimura, M. Kitagawa, T. Yamada et al., “C-reactive protein is a potential prognostic factor for metastatic gastric cancer,” Anticancer Reseach, vol. 32, no. 2, pp. 491–496, 2012. View at Google Scholar · View at Scopus
  9. U. Zingg, J. Forberger, B. Rajcic, C. Langton, and G. G. Jamieson, “Association of C-reactive protein levels and long-term survival after neoadjuvant therapy and esophagectomy for esophageal cancer,” Journal of Gastrointestinal Surgery, vol. 14, no. 3, pp. 462–469, 2010. View at Publisher · View at Google Scholar
  10. H. Miyata, M. Yamasaki, Y. Kurokawa et al., “Prognostic value of an inflammation-based score in patients undergoing pre-operative chemotherapy followed by surgery for esophageal cancer,” Experimental and Therapeutic Medicine, vol. 2, no. 5, pp. 879–885, 2011. View at Publisher · View at Google Scholar
  11. T. Kobayashi, K. Oshima, T. Yokobori et al., “Perioperative nutriture in esophageal cancer patients undergoing esophagectomy,” Hepato-Gastroenterology, vol. 60, no. 126, pp. 1311–1316, 2013. View at Google Scholar · View at Scopus
  12. X. Xu, H. Yu, W. Hu, Q. Song, and W. Mao, “A novel inflammation-based prognostic score, the C-reactive protein/albumin ratio predicts the prognosis of patients with operable esophageal squamous cell carcinoma,” PLoS ONE, vol. 10, no. 9, Article ID e138657., 2015. View at Publisher · View at Google Scholar
  13. X. Wei, F. Wang, D. Zhang et al., “A novel inflammation-based prognostic score in esophageal squamous cell carcinoma: the C-reactive protein/albumin ratio,” BMC Cancer, vol. 15, no. 1, article no 350, 2015. View at Publisher · View at Google Scholar
  14. K. Gonda, M. Shibata, Y. Sato et al., “Elevated neutrophil-to-lymphocyte ratio is associated with nutritional impairment, immune suppression, resistance to S-1 plus cisplatin, and poor prognosis in patients with stage IV gastric cancer,” Molecular and Clinical Oncology, pp. 1073–1078, 2017. View at Publisher · View at Google Scholar
  15. D. Unal, O. Orhan, C. Eroglu, and B. Kaplan, “Prealbumin is a more sensitive marker than albumin to assess the nutritional status in patients undergoing radiotherapy for head and neck cancer,” Współczesna Onkologia, vol. 3, pp. 276–280, 2013. View at Publisher · View at Google Scholar
  16. Y. Yang, Q. Shang, Y. Yuan, X. Wu, W. Hu, and L. Chen, “Comparison of long-term quality of life in patients with esophageal cancer after ivor-lewis, mckeown, or sweet Esophagectomy,” Journal of Gastrointestinal Surgery, vol. 23, no. 2, pp. 225–231, 2019. View at Publisher · View at Google Scholar
  17. D. P. Raymond, C. W. Seder, C. D. Wright et al., “Predictors of major morbidity or mortality after resection for esophageal cancer: A society of thoracic surgeons general thoracic surgery database risk adjustment model,” The Annals of Thoracic Surgery, vol. 102, pp. 207–214, 2016. View at Google Scholar
  18. H. Kato and M. Nakajima, “Treatments for esophageal cancer: a review,” General Thoracic and Cardiovascular Surgery, vol. 61, no. 6, pp. 330–335, 2013. View at Publisher · View at Google Scholar
  19. T. W. Rice, V. W. Rusch, H. Ishwaran, and E. H. Blackstone, “Cancer of the esophagus and esophagogastric junction: data-driven staging for the seventh edition of the American joint committee on cancer/international union against cancer staging manuals,” Cancer, vol. 116, no. 16, pp. 3763–3773, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. R. L. Camp, M. Dolled-Filhart, and D. L. Rimm, “X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization,” Clinical Cancer Research, vol. 10, no. 21, pp. 7252–7259, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Feng and Q. Chen, “Significance of the prognostic nutritional index in patients with esophageal squamous cell carcinoma,” Therapeutics and Clinical Risk Management, vol. 10, pp. 1–7, 2014. View at Publisher · View at Google Scholar
  22. H. Shimada, Y. Nabeya, S.-I. Okazumi et al., “Elevation of preoperative serum C-reactive protein level is related to poor prognosis in esophageal squamous cell carcinoma,” Journal of Surgical Oncology, vol. 83, no. 4, pp. 248–252, 2003. View at Publisher · View at Google Scholar · View at Scopus
  23. X. Yang, Y. Huang, J. F. Feng, and J. S. Liu, “Prognostic significance of neutrophil-to-lymphocyte ratio in esophageal cancer: a meta-analysis,” Onco Targets Therapy, vol. 8, pp. 789–794, 2015. View at Publisher · View at Google Scholar
  24. L. Li, L. Dai, X. Wang et al., “Predictive value of the C-reactive protein-to-prealbumin ratio in medical ICU patients,” Biomarkers in Medicine, vol. 11, no. 4, pp. 329–337, 2017. View at Publisher · View at Google Scholar
  25. J. Lu, B. B. X, Z. F. Zheng et al., “CRP/prealbumin, a novel inflammatory index for predicting recurrence after radical resection in gastric cancer patients: post hoc analysis of a randomized phase III trial,” Gastric Cancer, vol. 22, pp. 536–545, 2019. View at Google Scholar
  26. J. P. Geisler, G. C. Linnemeier, A. J. Thomas, and K. J. Manahan, “Nutritional assessment using prealbumin as an objective criterion to determine whom should not undergo primary radical cytoreductive surgery for ovarian cancer,” Gynecologic Oncology, vol. 106, no. 1, pp. 128–131, 2007. View at Publisher · View at Google Scholar
  27. L. T. Guerra, A. R. Rosa, R. F. Romani et al., “Serum transferrin and serum prealbumin as markers of response to nutritional support in patients with esophageal cancer,” Nutricion Hospitalaria, vol. 24, pp. 241-242, 2009. View at Google Scholar
  28. S. C. Wightman, M. C. Posner, M. G. Patti et al., “Extremes of body mass index and postoperative complications after esophagectomy,” Diseases of the Esophagus, vol. 30, no. 5, pp. 1–6, 2017. View at Publisher · View at Google Scholar
  29. J. Shapiro, J. J. van Lanschot, M. C. Hulshof et al., “Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial,” The Lancet Oncology, vol. 16, pp. 1090–1098, 2015. View at Google Scholar
  30. C. Mariette, L. Dahan, F. Mornex et al., “Surgery alone versus chemoradiotherapy followed by surgery for stage I and II esophageal cancer: Final analysis of randomized controlled phase III trial FFCD 9901,” Journal of Clinical Oncology, vol. 32, no. 23, pp. 2416–2422, 2014. View at Publisher · View at Google Scholar · View at Scopus