Variability of Oxaliplatin-Induced Neuropathic Pain Symptoms in Each Cycle and Its Implications on the Management of Colorectal Cancer Patients: A Retrospective Study in South Western Sydney Local Health District Hospitals, Sydney, Australia
Table 2
Baseline characteristics of study subjects.
Variable
Frequency (n)
Percentage (%)
Type of colorectal cancer
Adenocarcinoma of caecum
61
18.9
Adenocarcinoma of ascending colon
30
9.3
Adenocarcinoma of transverse colon
21
6.5
Adenocarcinoma of descending colon
10
3.1
Adenocarcinoma of sigmoid colon
109
33.9
Adenocarcinoma of rectosigmoid junction
28
8.7
Adenocarcinoma of rectum
63
19.6
Starting dose of oxaliplatin (IV) in the treatment regimen
85 mg/m2
214
66.5
100 mg/m2
5
1.6
130 mg/m2
103
32
Starting dose of fluorouracil in the treatment regimen
400 mg/m2 (IV) plus 2400 mg/m2 (CIVP)
211
65.5
NA
111
34.5
Starting dose of folinic acid (FA) in the treatment regimen
50 mg/m2
1
0.3
200 mg/m2
207
64.3
400 mg/m2
3
0.9
NA
111
34.5
Treatment regimen
Adjuvant: n (%)
Metastatic: n (%)
FOLFOX
144 (44.7)
67 (20.8)
XELOX
84 (26.1)
21 (6.5)
FOLFOX + avastin
1 (0.3)
0 (0)
Oxaliplatin alone
4 (1.2)
1 (0.3)
NA: not applicable; CIVP: central intravenous pump; IV=intravenous.