Research Article

Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches

Table 1

Summary of the clinical data for patients genomically profiled in this study (n = 41). Patients with IDH-wildtype and IDH-mutant glioblastoma tumours were identified from the BRASH clinical database between 2009 and 2014.

CharacteristicIDH-wildtypeIDH-mutant

Number of patients383
Age
 Mean5442
 Median (range)52 (16–78)50 (19–58)
Gender
 Male19 (50%)2 (66%)
 Female20 (50%)1 (33%)
 Survival range (months)2–485–12
Tumour location
 Temporal lobe8 (21%)2 (66%)
 Frontal lobe15 (39%)
 Parietal lobe4 (11%)
 Occipital4 (11%)
 More than one lobe5 (13%)1 (33%)
 Multifocal1 (3%)
 No data1 (3%)
Tumour recurrence
 Initial383
 Recurrent71