Journal of Oncology / 2019 / Article / Fig 4

Research Article

miR-199a-5p Represses Protective Autophagy and Overcomes Chemoresistance by Directly Targeting DRAM1 in Acute Myeloid Leukemia

Figure 4

Western blot assay of LC3-II/I and Beclin1 protein under treatment of 3-MA was performed in K562 (a) and K562/ADM cells (b) (n = 3, , ). (c) K562/ADM cell viability was examined using a CCK-8 assay under the combined treatment of ADM (140 μg/ml) and 3-MA. Nontreated K562/ADM cells were used as control (n = 3; ).