Colorectal Cancer Characteristics and Outcomes after Solid Organ Transplantation

Table 4

Summary of studies looking at solid-organ transplant and other cancers including colorectal cancers.

Author’s name	Year published	No. of transplant patients in study	Transplanted organ(s)	Cancer(s) developed	Registry
Merchea et al. [6]	2014	20	(i) Kidney	CRC	Mayo Clinic
			(ii) Liver		Cancer Registry
			(iii) Heart
			(iv) Lung
Rocha et al. [1]	2013	1695	Kidney	(i) CRC (21.2%)	Single center,
				(ii) Malignant	Portugal
				Lymphoma
				(16.7%)
				(iii) Breast cancer
				(13.6%)
Albright et al. [19]	2010	402	Liver	(i) CRC (n=3)	Single center,
				(ii) HPV-anal	California USA
				cancer (n=2)
				(iii) EBV-cecal
				lymphoproliferative
				cancer
				(n=1)
Carenco et al. [13]	2015	465	Liver	(i) Skin cancer	Single center,
				(n=28)	France
				(ii) PTLD (n=13)
				(iii) Oral cancer
				(n=17)
				(iv) Lung cancer
				(n=15)
				(v) CRC (n=8)
				(vi) Esophageal
				cancer (n=4)
				(vii) Anal cancer
				(n=2)
				(viii) Pancreatic
				cancer (n=1)
Aigner et al. [28]	2007	3595	(i) Kidney	(i) CRC (n=9,	Single center,
			(ii) Liver	0.25%)	Austria
			(iii) Pancreas	(ii) Anal cancer
			(iv) Heart	(n=4, 0.11%)
			(v) Lung	(iii) PTLD (n=5)
			(vi) Small bowel
Papaconstantinou	2004	150	(i) Kidney	CRC	Israel Penn
et al. [26]			(ii) Heart		International
			(iii) Liver		Transplant
			(iv) Lung		Tumor
					Registry, and
					National
					Cancer
					Institute SEER
Sint Nicolaas et al. [7]	2010	394	Liver	CRC (n=4, 1%)	Single center,
					Netherlands
Engels et al. [29]	2011	175,732	(i) Kidney (58.4%)	Non-Hodgkin	US Scientific
			(ii) Liver (21.6%)	lymphoma, Hodgkin	Registry of
			(iii) Heart (10.0%)	lymphoma, cancers of	Transplant
			(iv) Lung (4.0%)	stomach, liver, colon,	Recipients
				rectum, anus, oral	(1987-2008),
				cavity, vulva, cervix,	and 13 state
				penis, nasopharynx,	and regional
				vagina and others	cancer
					registries
Adami et al. [9]	2003	5931	(i) Kidney	Non-Hodgkin	National
			(ii) Liver	lymphoma, cancers of	cancer
				skin, lips, oral cavity,	database,
				esophagus, stomach,	Sweden
				colon, rectum, anus,
				vulva, vagina, lung,
				urinary bladder,
				thyroid cancer
Haagsma et al. [10]	2001	174	Liver	Cancers of skin, lip,	Single center,
				colon, kidney and B-	Netherlands
				cell lymphoma
Kyllönen et al. [11]	2000	2890	Kidney	Cancers of skin, lip,	National
				thyroid, kidney, lower	transplant and
				urinary tract, colon,	cancer
				ovary and Non-	registries,
				Hodgkin lymphoma	Finland
Kang et al. [15]	2018	348	Liver	CRC	Single center,
					Korea
Nordin et al. [16]	2018	4246	Liver	CRC, Non-Hodgkin lymphoma, skin cancer	Nordic liver transplant registry