Roles of the Phosphorylation of Transcriptional Factors in Epithelial-Mesenchymal Transition

Table 3

The posttranslational modification sites of Twist 1 for EMT.

Sites	Kinase/Enzyme	Function	Reference
Phosphorylation
S123/T148-p	AURKA	TF activity (Partner choice)	[39]
		Stabilization
		Homodimerization
S184-p	AURKA	TF activity (Direct)	[39]
		Stabilization
T125/S127-p	PKA	TF activity (Partner choice)	[40]
		Heterodimerization
S42-p	AKT1	TF activity	[41]
T121/S123-p	AKT1	Degradation	[42]
T125/S127-p	IKKβ	Degradation	[43]
		Cytoplasm translocalization
S18/S20-p	CK2	Stabilization	[44]
S68-p	P38, JNK, ERK1/2	Stabilization	[45]
Methylation
R34-Me	PRMT1	E-cadherin repression	[46]