Development and External Validation of Web-Based Models to Predict the Prognosis of Remnant Gastric Cancer after Surgery: A Multicenter Study

Table 2

Multivariable analyses for overall survival, disease-specific survival, and disease-free survival.

	Overall survival			Disease-specific survival			Disease-free survival
	Multivariate Model†			Multivariate Model†			Multivariate Model†
Variable	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
Age (year)			<0.001			0.008			0.005
>65	Ref			Ref			Ref
≤65	2.05	1.36-3.08	<0.001	1.86	1.18-2.93	0.008	1.77	1.20-2.64	0.005
Size (cm)			0.012			0.005			0.006
≤2	Ref			Ref			Ref
2-5	1.05	0.50-2.18	0.905	1.03	0.43-2.51	0.943	1.22	0.58-2.57	0.603
>5	1.87	1.20-2.93	0.006	2.17	0.95-4.93	0.065	1.96	1.28-3.01	0.002
T-stage			<0.001			<0.001			<0.001
T1	Ref			Ref			Ref
T2	2.19	0.67-7.16	0.195	3.08	0.64-14.85	0.161	2.54	0.78-8.28	0.122
T3	3.40	1.11-10.49	0.033	4.36	0.95-19.93	0.058	4.44	1.45-13.62	0.009
T4a	5.21	1.76-15.47	<0.001	7.40	1.68-32.58	0.008	6.19	2.07-18.48	0.001
T4b	9.36	2.98-29.44	<0.001	16.00	3.46-74.02	<0.001	12.87	4.05-40.94	<0.001
N-stage			<0.001			<0.001			0.001
N0	Ref			Ref			Ref
N1	1.42	0.78-2.60	0.258	1.39	0.71-2.71	0.337	1.32	0.74-2.34	0.349
N2	3.49	1.86-6.53	<0.001	3.49	1.80-6.80	<0.001	2.43	1.34-4.42	0.004
N3a	3.59	1.96-6.56	<0.001	3.70	1.88-7.27	<0.001	2.81	1.58-5.01	<0.001
N3b	6.72	2.31-19.57	<0.001	6.06	1.85-19.87	0.003	3.18	1.13-9.00	0.029

†Adjusted for age, sex, BMI, family history of gastric cancer, interval between gastrectomy and remnant gastric cancer, previous disease, previous operation type, reconstruction, comorbidity, complication, ASA score, tumor location, lymphovascular invasion, approach, combined resection, histology, macroscopic type, retrieved lymph node, complication, and adjuvant chemotherapy.