Development and External Validation of Web-Based Models to Predict the Prognosis of Remnant Gastric Cancer after Surgery: A Multicenter Study
Table 3
Comparison of the prognostic performances of the 3 studied staging systems and the web-based prognostic model.
Overall survival
AJCC7th staging
AJCC8th staging
TRM staging
Huang OS model
Harrell’s C index
0.743 (0.702-0.785)
0.732 (0.689-0.774)
0.744 (0.704-0.785)
0.774 (0.733-0.815)
P value
0.254
0.927
0.037
AIC†
1060.08
1064.41
1060.46
1042.71
Relative likelihood††
0.115
0.827
<0.001
Likelihood ratio chi-square‡
65.86
61.53
65.48
91.25
Disease-specific survival
AJCC7th staging
AJCC8th staging
TRM staging
Huang DSS model
Harrell’s C index
0.742 (0.700-0.784)
0.731 (0.687-0.775)
0.754 (0.714-0.796)
0.773 (0.730-0.817)
P value
0.408
0.290
0.032
AIC†
872.37
878.3
871.63
864.15
Relative likelihood††
0.052
0.691
0.016
Likelihood ratio chi-square‡
70.32
64.39
71.06
85.54
Disease-free survival
AJCC7th staging
AJCC8th staging
TRM staging
Huang DFS model
Harrell’s C index
0.710 (0.667-0.754)
0.700 (0.656-0.744)
0.714 (0.672-0.755)
0.744 (0.702-0.787)
P value
0.397
0.703
0.021
AIC†
1117.27
1123.18
1118.11
1109.79
Relative likelihood††
0.052
0.657
0.024
Likelihood ratio chi-square‡
72.49
64.58
71.66
84.98
AIC: Akaike information criterion. A higher Harrell’s C index indicates higher discriminative ability. P value of Harrell’s C index (compare with AJCC7th staging system). † Smaller AIC values indicate better optimistic prognostic stratification. †† The relative likelihood could be interpreted as a P value for the comparison of both AIC values (compare with AJCC7th staging system). ‡ A higher likelihood ratio chi-square score means better homogeneity.
