Direct Genetics Referral Pathway for High-Grade Serous Ovarian Cancer Patients: The “Opt-Out” Process

Table 5

Family history risk categories for patients with mutations in BRCA1/2.

BRCA positive (N=18)	N (14.6%)
Average Risk	10 (55.6%)
Moderate Risk	5 (27.8%)
High Risk	3 (16.6%)

Average Risk = no first- or second-degree relatives with breast or ovarian cancer.
Moderate Risk = one first-degree relative with breast or ovarian cancer or two first or second-degree relatives with pancreatic or prostate cancer.
High Risk = at least one first-degree and second-degree relative diagnosed with breast or ovarian cancer on the same side of the family or three or more first- or second-degree relatives with breast, ovarian, prostate, or pancreatic cancer.