Liver Metastases and Histological Growth Patterns: Biological Behavior and Potential Clinical Implications—Another Path to Individualized Medicine?

<div>Schematic representation of the Growth Patterns of Colorectal Liver Metastases, adapted from Temido MJ (2018) Clinical and Pathological Factors of Prognosis after Hepatectomy for Gastric Cancer Liver Metastases. Is desmoplastic growth the key to longer survival? Master Thesis in Medicine, with permission. (a) Desmoplastic Growth Pattern: the tumor is separated from the liver parenchyma by a band of fibrous tissue, which contains tumor infiltrating lymphocytes; (b) Replacement Growth Pattern: the tumor permeates between the liver hepatocytes, without disruption of the normal architecture; (c) Pushing Growth Pattern: the tumor expands and compresses the surrounding hepatocytes.</div>

Journal of Oncology

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Figure 1: Liver Metastases and Histological Growth Patterns: Biological Behavior and Potential Clinical Implications—Another Path to Individualized Medicine? 

Figure 1 | Liver Metastases and Histological Growth Patterns: Biological Behavior and Potential Clinical Implications—Another Path to Individualized Medicine? 