Research Article
Transarterial Chemoembolization Combined with Radiofrequency Ablation in the Treatment of Stage B1 Intermediate Hepatocellular Carcinoma
Table 4
Subgroup analysis of survivals.
| | TACE-RFA | TACE | value | 1-year (%) | 3-year (%) | 5-year (%) | Median time (months) | 1-year (%) | 3-year (%) | 5-year (%) | Median time (months) |
| Overall survival | Tumor size ≤3 cm | 88.8 | 51.3 | 30.8 | 37.6 | 80.5 | 31.8 | 23.8 | 26.0 | 0.024 | Tumor size >3 cm | 75.0 | 37.9 | 14.3 | 29.8 | 75.5, | 18.8 | 11.0 | 19.0 | 0.053 | Single tumor | 86.2 | 53.9 | 28.4 | 37.8 | 75.2 | 27.1 | 17.6 | 23.0 | 0.016 | Multiple tumors | 82.8 | 42.7 | 23.4 | 29.8 | 73.5 | 26.0 | 13.6 | 22.0 | 0.051 |
| Progression-free survival | Tumor size ≤3 cm | 75.2 | 32.1 | 15.3 | 21.9 | 66.6 | 14.9 | 3.1 | 15.0 | <0.001 | Tumor size >3 cm | 66.7 | 18.4 | 9.9 | 18.0 | 54.8 | 8.7 | 0 | 13.0 | 0.008 | Single tumor | 79.3 | 31.9 | 17.2 | 21.0 | 59.7 | 14.3 | 4.8 | 14.2 | 0.001 | Multiple tumors | 69.5 | 24.5 | 11.6 | 19.0 | 55.9 | 9.4 | 0 | 13.8 | <0.001 |
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TACE: transarterial chemoembolization; RFA: radiofrequency ablation.
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