|
| Authors/reference #/year | WHO performance status | Drug vs Preoperative chemoradiotherapy (CRT) | Differentiation status | Length of tumor | Histology/ squamous cell carcinoma (SCC)
| Location of tumor
|
|
Robb W.B. et al.
/[4]/2015 | ≥1 vs 0
locoregional recurrence
HR:0.97(0.46,2.04)
metastatic recurrence
0·67 (0·31, 1·43) | nCRTs vs surgery only
Univariable
HR:0.80(0.45-1.43)
Mulivariable
HR:1.03(0.56-1.93)
P:0.917 | - | - | Adenocarcinoma vs SCC
HR:0.96(0.47-1.96) | Below vs above carina
HR:1.09(0.34-3.52) |
|
Zhao Y, et al.
/[5]/2015 | 0 HR:0.85(0.69 -1.04)
1
HR:0.97(0.76-1.23) | Perioperative vs preoperative
5-year relapse free HR:0.62(0.49-0.73)
HR for death:0.79(0.59-0.95) | - | ≥8.0cm
HR:0.95(0.73-1.24)
<8.0cm
HR; 0.86(0.71-1.04) | - | Upper/middle
HR:0.86(0.66-1.13)
Lower
HR:0.89(0.73-1.08) |
|
| Dutton S.J. et al. /[2]/2014 | 0
HR:0.67(0.46-0.98)
1
HR:0.83(0.64-1.08)
2
HP:0.81(0.54-1.23) | Overall survival
Gefitinib vs placebo
HR:0.90 | - | - | Adenocarcinoma
HR:0.81(0.65-1.01)
Squamous cell
HR:0.72(0.48-1.08) | Oesophageal
HR:0.83(0.64-0.99)
Junctional I/II
HR:0.73(0.48-1.09) |
|
Oppedijk V. et al.
/[7]/2014 | | Treatment arm(S vs S+CRT)
Univariable HR:0.37(0.23-0.59)
Multivariable HR:0.50(0.29-0.86)
| - | ≤5 cm vs >5cm
HR:0.89(0.54-1.46) | SCC vs AC
Univariable
HR:0.70(0.44-1.12)
Mulivariable
HR:0.49(0.29-0.82) | - |
|
| Swisher S.G. et al. [8]/2010 | 1 vs 0
HR:1.24(0.91-1.70) | Preoperative C/RT vs preoperative C
Overall survival HR:0.58(0.37-0.90)
Disease free survival HR:0.55(0.35-0.85) | Well/moderate
HR:1.0
Poor/undifferentiated
HR:1.3 P:0.2
Unknown
HR:1.1 P:0.7 | - | - | Upper/middle
HR:1.0
Lower
HR:0.8(0.5-1.4) |
|
| Crehange G. et al./[9]/2007 | - | P-RT vs SC-RT
Univariable HR:0.87(0.68-1.11)
Multivariable HR:0.83(0.63-1.08) | Dysphagia:grades 1-3 vs grades 4-5
HR:1.22(0.88-1.68) | HR:1.03(1.01-1.05)
P:0.001 | - | - |
|
| Burmeister B.H. et al./[10]/2005 | 1 vs 0
HR:1.24(0.91-1.70) | CRT+S vs
S
PFS HR:0.82(0.61-1.10)
Overall survival HR:0.89(0.67-1.19) | Well/moderate
HR:0.69(0.43-1.12)
Poor
HR:0.92(0.59-1.45) | >5cm
HR:0.72(0.44-1.17)
≤5cm
HR:0.83(0.57-1.21) | Squamous
HR:0.47(0.25-0.86)
Non-squamous
HR:1.02(0.72-1.44) | Lower
HR:0.97(0.70-1.33)
Middle or upper
HR:0.38(0.17-0.87) |
|
