Research Article

Long Non-Coding RNA Expression Profile Associated with Malignant Progression of Oral Submucous Fibrosis

Figure 2

Structure comparison of lncRNAs and mRNAs in the malignant progression of OSF. Distribution of the number of (a) length and exons, as well as (b) FPKM of lncRNAs and mRNAs. (c) The cluster analysis of expression levels of transcripts in 18 tissue samples (2 normal mucous, 8 OSF and 8 OSCC samples). (d) PCA diagram shows separate expression pattern during OSF progression to OSCC, through analyzing lncRNA expression levels in normal mucous, OSF and OSCC samples, localized to Normal (red), OSF (green) and OSCC (yellow).