TDG Gene Polymorphisms and Their Possible Association with Colorectal Cancer: A Case Control Study

Table 5

Genotype frequencies of TDG gene polymorphisms in colorectal cases and controls in the below-57-year-old group.

SNP	Variant	Patients Cases	Controls	OR	CI	χ^2 Value	p-value
rs4135050	TT	31 (0.58)	67 (0.68)	Ref
	TA	19 (0.36)	25 (0.25)	1.643	0.789–3.418	1.78	0.18271
	AA	3 (0.06)	7 (0.07)	0.926	0.224–3.824	0.01	0.91567
	TA+AA	22 (0.42)	32 (0.32)	1.486	0.745–2.962	1.27	0.25944
	T	81 (0.76)	159 (0.80)	Ref
	A	25 (0.24)	39 (0.20)	1.258	0.712–2.223	0.63	0.42813
rs1882018	CC	30 (0.57)	61 (0.62)	Ref
	CT	17 (0.32)	31 (0.31)	1.115	0.534–2.327	0.08	0.77161
	TT	6 (0.11)	7 (0.07)	1.743	0.538–5.642	0.87	0.34986
	CT+TT	23 (0.43)	38 (0.38)	1.231	0.625–2.423	0.36	0.54797
	C	77 (0.73)	153 (0.77)	Ref
	T	29 (0.27)	45 (0.23)	1.281	0.745–2.200	0.80	0.36989
rs4135066	CC	2 (0.04)	9 (0.09)	Ref
	CT	21 (0.40)	31 (0031)	3.048	0.598–15.547	1.93	0.16466
	TT	30 (0.56)	59 (0.60)	2.288	0.465–11.265	1.08	0.29768
	CT+TT	51 (0.96)	90 (0.91)	2.550	0.530–12.260	1.45	0.22791
	C	25 (0.24)	49 (0.25)	Ref
	T	81 (0.76)	149 (0.75)	1.066	0.613–1.851	0.05	0.82191
rs3751209	GG	26 (0.49)	46 (0.46)	Ref
	GA	20 (0.38)	44 (0.44)	0.804	0.394–1.643	0.36	0.54978
	AA	7 (0.13)	9 (0.10)	1.376	0.459–4.128	0.33	0.56807
	GA+AA	27 (0.51)	53 (0.54)	0.901	0.462–1.758	0.09	0.76037
	G	72 (0.68)	136 (0.69)	Ref
	A	34 (0.32)	62 (0.31)	1.036	0.624–1.719	0.02	0.89161
rs1866074	AA	13 (0.25)	13 (0.13)	Ref
	AG	22 (0.42)	42 (0.42)	0.524	0.208–1.322	1.90	0.16815
	GG	18 (0.33)	44 (0.43)	0.409	0.159–1.052	3.53	0.06029
	AG+GG	40 (0.75)	86 (0.87)	0.465	0.198–1.094	3.16	0.07536
	A	48 (0.45)	68 (0.34)	Ref
	G	58 (0.55)	130 (0.66)	0.632	0.390–1.023	3.50	0.06132
rs4135113	GG	41 (0.77)	80 (0.81)	Ref
	GA	10 (0.19)	17 (0.17)	1.148	0.482–2.732	0.10	0.75528
	AA	2 (0.04)	2 (0.02)	1.951	0.265–14.35	0.45	0.50442
	GA+AA	12 (0.23)	19 (0.19)	1.232	0.546–2.784	0.25	0.61496
	G	92 (0.87)	177 (0.89)	Ref
	A	14 (0.13)	21 (0.11)	1.283	0.623–2.639	0.46	0.49826