TDG Gene Polymorphisms and Their Possible Association with Colorectal Cancer: A Case Control Study

Table 6

Genotype frequencies of TDG gene polymorphisms in colorectal cases and controls in the above-57-year-old group.

SNP	Variant	Patients Cases	Controls	OR	CI	χ^2 Value	p-value
rs4135050	TT	27 (0.57)	57 (0.62)	Ref
	TA	15 (0.32)	30 (0.33)	1.056	0.488–2.281	0.02	0.89062
	AA	5 (0.11)	5 (0.05)	2.111	0.563–7.914	1.27	0.25994
	TA+AA	20 (0.43)	35 (0.38)	1.206	0.590–2.466	0.26	0.60699
	T	69 (0.73)	144 (0.78)	Ref
	A	25 (0.27)	40 (0.22)	1.304	0.733–2.321	0.82	0.36543
rs1882018	CC	28 (0.60)	57 (0.62)	Ref
	CT	15 (0.32)	28 (0.30)	1.091	0.503–2.363	0.05	0.82605
	TT	4 (0.08)	7 (0.08)	1.163	0.314–4.307	0.05	0.82075
	CT+TT	19 (0.40)	35 (0.38)	1.105	0.539–2.267	0.07	0.78518
	C	71 (0.76)	142 (0.77)	Ref
	T	23 (0.24)	42 (0.23)	1.095	0.612–1.962	0.09	0.75960
rs4135066	CC	2 (0.04)	5 (0.05)	Ref
	CT	17 (0.36)	27 (0.29)	1.574	0.274–9.045	0.26	0.60894
	TT	28 (0.60)	60 (0.65)	1.167	0.213–6.387	0.03	0.85883
	CT+TT	45 (0.94)	87 (0.95)	1.293	0.241–6.930	0.09	0.76356
	C	21 (0.22)	37 (0.20)	Ref
	T	73 (0.78)	147 (0.80)	0.875	0.478–1.602	0.19	0.66485
rs3751209	GG	25 (0.53)	41 (0.45)	Ref
	GA	18 (0.38)	44(0.47)	0.671	0.320–1.407	1.12	0.28959
	AA	4 (0.09)	7 (0.08)	0.937	0.249–3.527	0.01	0.92351
	GA+AA	22 (0.47)	51 (0.55)	0.707	0.349–1.432	0.93	0.33531
	G	68 (0.72)	126 (0.68)	Ref
	A	26 (0.28)	58 (0.32)	0.831	0.480–1.438	0.44	0.50706
rs1866074	AA	9 (0.19)	11 (0.12)	Ref
	AG	17 (0.36)	4 (0.43)	0.519	0.182–1.481	1.52	0.21694
	GG	21 (0.45)	41 (0.45)	0.626	0.224–1.747	0.81	0.36892
	AG+GG	38 (0.81)	81 (0.88)	0.573	0.219–1.500	1.31	0.25305
	A	35 (0.37)	62 (0.34)	Ref
	G	59 (0.63)	122 (0.66)	0.857	0.510–1.438	0.34	0.55817
rs4135113	GG	34 (0.72)	76 (0.83)	Ref
	GA	8 (0.17)	14 (0.15)	1.277	0.490–3.33	0.25	0.61607
	AA	5 (0.11)	2 (0.02)	5.588	1.032–30.254	4.86	0.02745
	GA+AA	13 (0.28)	16 (0.17)	1.816	0.787–4.191	1.99	0.15870
	G	76 (0.81)	166 (0.90)	Ref
	A	18 (0.19)	18 (0.10)	2.184	1.077–4.431	4.84	0.02778