IL-2 Induces Transient Arrest in the G1 Phase to Protect Cervical Cancer Cells from Entering Apoptosis

Figure 1

Presence of the alpha, beta, and gamma subunits (IL-2R) in the cervical cancer cell lines HeLa and INBL. The expression of the IL-2R subunits was determined using specific antibodies for the alpha, beta, and gamma subunits by flow cytometry on a FACSAria II cytometer (BD, USA). The histograms corresponding to the HeLa cell line (a) and the INBL cell line (b) are shown. We defined the gate for positive events such that all negative controls (isotypes) represented 1% of events. Then, this gate was applied to all the conditions. Representative flow cytometry plots of one out of three independent experiments. (c) The graph representation of the basal expression compared to the expression after the stimulation with IL-2 is shown. The expression of the IL-2R subunits is statistically significant. , . Results are the median of three independent experiments.

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