Journal of Oncology / 2019 / Article / Fig 1

Research Article

Circular RNA hsa_circRNA_0007334 is Predicted to Promote MMP7 and COL1A1 Expression by Functioning as a miRNA Sponge in Pancreatic Ductal Adenocarcinoma

Figure 1

circRNA expression profile in PDAC. (a) The volcano plot was constructed according to the fold change and p value. The x-axis presents the log2(fold change) value of differential expression, and the y-axis presents the -log10(padj) value of differential expression. The vertical lines correspond to 2.0-fold up- and downregulation between PDAC and adjacent nontumor tissues, and the horizontal line represents a p value of 0.05. The red circles in the plot represent the upregulated circRNAs, and the green circles in the plot represent the downregulated differentially expressed circRNAs with statistical significance. (b) Hierarchical clustering analysis of circRNAs that were differentially expressed (over a 2.5-fold change) between PDAC and adjacent nontumor tissues. The x-axis presents samples (N1-N5: adjacent nontumor tissues; T1-T5: PDAC tissues), and the y-axis presents the differentially expressed circRNAs. Expression values are represented in different colors; red indicates a high expression level, and blue indicates a low expression level.

(a)
(b)

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.