Current Landscape of Epigenetics in Lung Cancer: Focus on the Mechanism and Application

Figure 1

Genomic changes associated with the progression of lung cancer. Tumorigenesis involves a multistep process resulting from the interactions of genetic, epigenetic, and environmental factors. The progression from normal lung tissue to malignant phenotype is accompanied by alterations in these three factors. (a) Morphological changes. (b) Genomic changes.

(a)

(b)