Can We Identify or Exclude Extensive Axillary Nodal Involvement in Breast Cancer Patients Preoperatively?

Table 4

Summary of studies on 18F-FDG PET/CT to exclude patients with extensive nodal involvement.

Study	Year	No. of patients	No. (%) of patients with extensive nodal involvement	No. of false negatives	No. of true negatives	NPV (%)	FNR (%)
Study in which extensive nodal involvement was defined as pN2-3
Hwang et al. [40]	2013	349	18 (5.2%)	5	288	98	28
Study in which extensive nodal involvement was defined as ≥3 positive nodes
Ahn et al. [32]	2017	364	43 (11.8%)	9	250	97	21

No. of false negatives = number of patients with normal/negative PET/CT but histologically extensive nodal involvement; no. of true negatives = number of patients with normal/negative PET/CT and histologically no/limited nodal involvement; NPV = negative predictive value; FNR = false-negative rate.