EF24 Suppresses Cholangiocellular Carcinoma Progression, Inhibits STAT3 Phosphorylation, and Induces Apoptosis via ROS-Mediated Oxidative Stress

Figure 2

EF24 induces apoptosis in cholangiocarcinoma cells in vitro. EF24 significantly induced apoptosis in SNU478 and HuCC-T1 cell lines determined by flow cytometry analysis of Annexin V positive cells (a) as well as by Western blot analysis (b). The bar diagrams show quantification of Western blot results; “” stands for p<0.05; “” stands for p<0.01 as compared to mock-treated control.

(a)

(b)