The Role of MicroRNA in Paediatric Acute Lymphoblastic Leukaemia: Challenges for Diagnosis and Therapy

Figure 2

Major recurrent chromosome aberrations of childhood BCP-ALL. Hyperdiploidy and the ETV6-RUNX1 translocation constitute the major subgroups of BCP-ALL and are associated with favourable clinical outcome. The t(1;19) and “B-Others” subgroups are associated with intermediate risk and the remaining subgroups are deemed poor risk.