Research Article

AURKA rs8173 G>C Polymorphism Decreases Wilms Tumor Risk in Chinese Children

Table 2

Stratification analysis of AURKA rs8173 genotypes with Wilms tumor susceptibility.

Variablesrs8173 (cases/controls)OR (95% CI)AOR (95% CI)a
GGGC/CC

Age (months)
 ≤1834/9731/1360.65 (0.37–1.13)0.1270.65 (0.38–1.13)0.128
 >1837/9941/1990.55 (0.33–0.91)0.0210.56 (0.34–0.93)0.024
Gender
 Female31/9233/1410.70 (0.40–1.21)0.1990.70 (0.40–1.22)0.203
 Male40/10439/1940.52 (0.32–0.86)0.0110.54 (0.33–0.90)0.017
Clinical stages
 I + II25/19628/3350.66 (0.37–1.16)0.1440.71 (0.40–1.26)0.245
 III + IV41/19640/3350.57 (0.36–0.91)0.0190.56 (0.35–0.90)0.017

OR, odds ratio; CI, confidence interval; AOR, adjusted odds ratio. aAdjusted for age and gender, without the corresponding stratification factor.