Galectin-3 Regulates the Expression of Tumor Glycosaminoglycans and Increases the Metastatic Potential of Breast Cancer

Figure 8

Schematic illustration of the overall findings. (a) The absence of Gal-3 in the microenvironment increased the number of the tumor cells but not its ability to migrate to the bone marrow. (b) In contrast, the low level of intracellular Gal-3 in tumor cells modified not only the migratory capacity of cells but also the number of metastatic cells in a bone marrow.

(a)

(b)