Circular RNA hsa_circ_0007142 Is Upregulated and Targets miR-103a-2-5p in Colorectal Cancer
Table 4
Correlation between hsa_circ_0007142 expression and clinicopathological characteristics of CRC.
Clinical Parameter
Hsa_circ_0007142 ()
Chi-squared test
High group
Low group
P value
(≥1, n=33)
(<1, n=17)
Gender
0.623
Male
21
12
Female
12
5
Age (years)
0.209
≤50
6
7
50–70
15
6
> 70
12
4
Tumor size
0.577
≤3 cm
8
5
3–5 cm
17
10
>5 cm
8
2
Differentiation
0.008
Poor
2
6
Moderate
24
11
Well
7
0
Lymphatic metastasis
0.037
Nx&N0
13
12
N1&N2
20
5
Tumor stage
0.136
I–II
19
6
III–IV
14
11
Distant metastasis
0.11
No
33
15
Yes
0
2
P<0.05, P<0.01. ΔCT is the difference between the CT value of hsa_circ_0007142 and of GAPDH. ΔΔCT is the difference between the ΔCT of CRC tissues and the ΔCT of adjacent normal tissues.