Research Article
Incorporating the Number of PLN into the AJCC Stage Could Better Predict the Survival for Patients with NSCLC: A Large Population-Based Study
Table 2
Influence of different variables on overall survival (OS) by pN stage for patients with NSCLC analyzed by Cox proportional hazard model.
| Variables | Univariate analysis | Multivariate analysis | Wald χ2 | | HR (95% CI) | |
| Age | 286.45 | <0.001 | | <0.001 | < 65 | | | Reference | | ≥ 65 | | | 1.578 (1.497–1.664) | <0.001 |
| Race | 18.08 | <0.001 | | <0.001 | White | | | Reference | | Black | | | 1.019 (0.927–1.121) | 0.691 | Others | | | 0.799 (0.719–0.887) | <0.001 |
| Sex | 134.46 | <0.001 | | <0.001 | Female | | | Reference | | Male | | | 1.359 (1.290–1.431) | <0.001 |
| Histology | 48.72 | <0.001 | | <0.001 | Squamous | | | Reference | | Adenocarcinoma | | | 0.831 (0.789–0.875) | <0.001 |
| pT stage | 273.10 | <0.001 | | <0.001 | pT1 | | | Reference | | pT2 | | | 1.345 (1.267–1.429) | <0.001 | pT3 | | | 1.951 (1.770–2.151) | <0.001 | pT4 | | | 1.837 (1.679–2.011) | <0.001 |
| pN stage | 633.92 | <0.001 | | <0.001 | pN0 | | | Reference | | pN1 | | | 1.630 (1.534–1.733) | <0.001 | pN2 | | | 2.157 (2.023–2.300) | <0.001 | pN3 | | | 2.799 (1.983–3.949) | <0.001 |
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