Incorporating the Number of PLN into the AJCC Stage Could Better Predict the Survival for Patients with NSCLC: A Large Population-Based Study

Table 3

Influence of different variables on overall survival (OS) for patients by nN stage with NSCLC analyzed by Cox proportional hazard model.

Variables	Univariate analysis		Multivariate analysis
	Wald χ^2		HR (95% CI)
Age	269.89	<0.001		<0.001
< 65			Reference
≥ 65			1.555 (1.475–1.639)	<0.001
Race	17.84	<0.001		<0.001
White			Reference
Black			1.022 (0.930–1.124)	0.649
Others			0.801 (0.721–0.889)	<0.001
Sex	137.28	<0.001		<0.001
Female			Reference
Male			1.363 (1.294–1.435)	<0.001
Histology	49.25	<0.001		<0.001
Squamous			Reference
Adenocarcinoma			0.831 (0.789–0.875)	<0.001
pT stage	286.01	<0.001		<0.001
pT1			Reference
pT2			1.340 (1.261–1.422)	<0.001
pT3			1.967 (1.785–2.169)	<0.001
pT4			1.870 (1.709–2.046)	<0.001
nN stage	696.79	<0.001		<0.001
nN0			Reference
nN1–3			1.657 (1.564–1.756)	<0.001
nN4-			2.371 (2.213–2.540)	<0.001