Research Article
Incorporating the Number of PLN into the AJCC Stage Could Better Predict the Survival for Patients with NSCLC: A Large Population-Based Study
Table 3
Influence of different variables on overall survival (OS) for patients by nN stage with NSCLC analyzed by Cox proportional hazard model.
| Variables | Univariate analysis | Multivariate analysis | Wald χ2 | | HR (95% CI) | |
| Age | 269.89 | <0.001 | | <0.001 | < 65 | | | Reference | | ≥ 65 | | | 1.555 (1.475–1.639) | <0.001 |
| Race | 17.84 | <0.001 | | <0.001 | White | | | Reference | | Black | | | 1.022 (0.930–1.124) | 0.649 | Others | | | 0.801 (0.721–0.889) | <0.001 |
| Sex | 137.28 | <0.001 | | <0.001 | Female | | | Reference | | Male | | | 1.363 (1.294–1.435) | <0.001 |
| Histology | 49.25 | <0.001 | | <0.001 | Squamous | | | Reference | | Adenocarcinoma | | | 0.831 (0.789–0.875) | <0.001 |
| pT stage | 286.01 | <0.001 | | <0.001 | pT1 | | | Reference | | pT2 | | | 1.340 (1.261–1.422) | <0.001 | pT3 | | | 1.967 (1.785–2.169) | <0.001 | pT4 | | | 1.870 (1.709–2.046) | <0.001 |
| nN stage | 696.79 | <0.001 | | <0.001 | nN0 | | | Reference | | nN1–3 | | | 1.657 (1.564–1.756) | <0.001 | nN4- | | | 2.371 (2.213–2.540) | <0.001 |
|
|