Journal of Oncology / 2020 / Article / Tab 2

Research Article

Comparison of Transcatheter Arterial Chemoembolization-Radiofrequency Ablation and Transcatheter Arterial Chemoembolization Alone for Advanced Hepatocellular Carcinoma with Macrovascular Invasion Using Propensity Score Analysis: A Retrospective Cohort Study

Table 2

Baseline characteristics of patients after matching.

VariablesTACEControl valueTACE + RFAControl value
(n = 188)(n = 188)(n = 102)(n = 102)

Median age (range)55 (25–78)54 (25–81)0.655a)57 (28–78)53 (25–80)0.068a)
Sex (M/F)164/24160/280.500b)84/1890/120.236b)
Family history of HCC (yes/no)24/16425/1630.878b)10/9215/870.286b)
HBV related (yes/no)169/19174/140.362b)93/994/80.800b)
GGT (IU/L)169.4 (86.8–190.4)197.9 (83.2–275.3)0.141c)101.5 (59.7–156.4)112.2 (60.4–185.3)0.711c)
WBC (×109/L)5.0 (3.4–5.8)5.1 (3.5–6.4)0.319c)4.5 (3.6–6.7)5.2 (3.8–6.3)0.955c)
PLT (×109/L)112.6 (61.7–143.8)126.9 (70.3–162.3)0.027c)111.8 (63.1–161.5)108.7 (69.9–164.4)0.898c)
AFP (ng/mL) (≥400/<400)90/9888/1000.836b)44/5841/610.670b)
PVTT (%)154 (81.9)147 (78.2)0.480b)83 (81.4)85 (83.3)0.713b)
HVTT (%)11 (5.9)12 (6.4)1.000b)6 (5.9)6 (5.9)1.000b)
PVTT + HVTT (%)23 (12.2)29 (15.4)0.535b)13 (12.7)11 (10.8)0.663b)
Tumor number (≥3/<3)92/96103/850.256b)41/6138/640.666b)
Tumor diameter (cm) (≥5/<5)109/79122/660.167b)56/4667/350.115b)
Child-Pugh class (A/B or C)79/10966/1220.168b)53/4950/520.674b)
MELD score6.8 (4.4–8.8)7.7 (4.8–9.6)0.672c)6.4 (3.4–8.8)7.4 (4.6–9.3)0.079c)
TNM (III/IV)153/35155/330.789b)88/1488/141.000b)
BCLC (C/D)160/28162/260.769b)92/1087/150.286b)

Age is presented as median (range), categorical variables as number (%), continuous variable as mean (interquartile range). a), t-test; b), chi-square test or Fisher’s exact test; c), Mann–Whitney U test. HBV, hepatitis B virus; GGT, gamma-glutamyl transferase; WBC, white blood cell count; PLT, platelet count; AFP, α-fetoprotein; PVTT, portal vein tumor thrombosis; HVTT, hepatic vein tumor thrombosis; MELD, model for end-stage liver disease; TNM, tumor, node, and metastasis staging; BCLC, Barcelona Clinic for Liver Cancer.

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