Computational Identification of Tumor Suppressor Genes Based on Gene Expression Profiles in Normal and Cancerous Gastrointestinal Tissues

Figure 1

The analysis pipeline for identifying tumor promoter genes (TPGs) and tumor suppressor genes (TSGs). The differentially expressed genes (DEGs) between two classes of samples were identified using the threshold of Student’s t-test adjusted value (FDR) <0.05 and mean gene-expression fold-change >1.5. The FDR was calculated by the Benjamini and Hochberg (BH) method [6]. SI: small intestine; FDR: false discovery rate.