Computational Identification of Tumor Suppressor Genes Based on Gene Expression Profiles in Normal and Cancerous Gastrointestinal Tissues

Figure 5

Correlations of the expression levels of tumor suppressor genes (TSGs) with immune cell infiltration levels in cancer. The RASGRP2 expression levels were positively associated with the enrichment levels of immune cells (CD8+ T cells and dendritic cells) in multiple TCGA cancer types/subtypes. Spearman’s rank correlation test values and correlation coefficients are shown. RSEM : RNA-Seq by Expectation Maximization [8].