Nomogram for Predicting Long-Term Survival after Synchronous Resection for Hepatocellular Carcinoma and Inferior Vena Cava Tumor Thrombosis: A Multicenter Retrospective Study

Table 3

Cox proportional hazards regression model showing the association of characteristics with survival.

Characteristics	Univariate model			Multivariate model
		HR	CI95		HR	CI95
Age (years)	0.58	0.99	0.97–1.02
Gender (M/F)	0.45	1.44	0.56–3.67
AFP (μg/ml)
<400			1.00 (reference)		1.00 (reference)
≥400	0.023	3.89	1.19–9.69	0.046	3.16	1.02–9.81
ALT (μ/l)	0.17	0.99	0.97–1.07
ALB (g/L)	0.43	1.03	0.96–1.11
PT (s)	0.28	1.13	0.91–1.40
Plt (×10…9/l)	0.56	1.00	0.99–1.00
Tumor size (cm)
<10		1.00 (reference)			1.00 (reference)
≥10	<0.001	3.72	1.88–7.37	0.043	2.20	1.02–4.74
Tumor number (solitary/multiple)	0.29	1.40	0.75–2.61
Differentiation	0.37	0.76	0.42–1.38
Child–Pugh grade (A/B)	0.009	3.26	1.35–7.88	0.63	1.44	0.33–6.26
TBil (μmol/l)	0.047	1.03	1–1.05	0.17	1.03	0.99–1.07
ECOG performance status (0/1)	<0.001	3.51	1.82–6.77	0.004	2.72	1.37–5.40
PVTT (positive/negative)	0.009	2.27	1.23–4.17	0.002	3.13	1.52–6.41
IVCTT classification
ID		1.00 (reference)			1.00 (reference)
SD	0.015	2.39	1.18–2.85	0.25	1.60	0.71–3.60
IC	<0.001	6.85	4.84–16.49	0.001	5.76	2.06–16.07