Clinical and Survival Impact of Sex-Determining Region Y-Box 2 in Colorectal Cancer: An Integrated Analysis of the Immunohistochemical Study and Bioinformatics Analysis

Table 2

Summary of results from this meta-analysis.

Variables	OR [95% CI]	Heterogeneity (p)	t value	value	Studies	Cases
Age (≥60 vs. < 60 years)	0.80 [0.13, 4.77]	0.618	−1.621	0.352	2	530
Gender (male vs. female)	0.91 [0.51, 1.64]	0.138	−0.439	0.684	5	991
MSI status (MSI vs. MSS)	1.40 [0.66, 3.00]	0.513	1.422	0.25	4	775
Clinical stage (stages 3-4 vs. 1-2)	1.34 [0.32, 5.64]	0.028	0.647	0.564	4	619
Histological grade (grades 3-4 vs. 1-2)	1.65 [0.62, 4.33]	0.004	1.428	0.227	5	999
Tumor size (≥5 vs. ≤5 cm)	0.78 [0.00, 1913.29]	0.018	−0.398	0.759	2	347
pT-stage (T 3-4 vs. 1-2)	1.12 [0.36, 3.43]	0.065	0.308	0.778	4	526
Lymph node metastasis (yes vs. no)	3.19 [0.58, 17.66]	0.368	2.916	0.1	3	225
Distal metastasis (yes vs. no)	1.26 [0.14, 10.91]	0.015	0.454	0.694	3	438

OR: odds ratio; CI: confidence interval; MSI: microsatellite instability; MSS: microsatellite stability.