Clinical and Survival Impact of Sex-Determining Region Y-Box 2 in Colorectal Cancer: An Integrated Analysis of the Immunohistochemical Study and Bioinformatics Analysis

Table 3

Correlation of SOX2 with the clinicopathological characteristics from the cancer genome atlas.

Variables	Comparison	OR with 95% CI		Cases
Age	≥60 vs. <60 years	1.03 (0.73–1.46)	0.859	618
Gender	Male vs. female	0.69 (0.5–0.94)	0.02	618
MSI status	MSI vs. MSS	1.08 (0.77–1.52)	0.663	618
Clinical stage	Stages 3-4 vs. 1-2	1.37 (0.99–1.89)	0.059	598
Venous invasion	Yes vs. no	1.12 (0.75–1.65)	0.585	536
Lymphatic invasion	Yes vs. no	1.27 (0.91–1.79)	0.162	557
Lymph node metastasis	Yes vs. no	1.37 (0.99–1.88)	0.057	615
Distal metastasis	Yes vs. no	1.13 (0.72–1.79)	0.597	545

OR: odds ratio; CI: confidence interval; MSI: microsatellite instability; MSS: microsatellite stability.