Morphological Characteristics and Clinical Significance of Different Types of Tumor Vessels in Patients with Stages I-IIA of Squamous Cervical Cancer

Table 2

The frequency of cervical cancer recurrence depending on the disease clinical and pathological characteristics.

Clinical and pathological data	Cervical cancer recurrence
	Absence		Presence
	n	%	n	%
Age (years)
<35	4	23.5	13	76.5	0.02
35–44	1	3.1	31	96.9
≥45	0	0	15	100.0
Stages
IA	1	3.6	27	96.4	0.33
IB	4	12.9	27	87.1
IIА	0	0	5	100.0
Histology
Squamous cell keratinous carcinoma	4	18.2	18	81.8	0.03
Squamous cell nonkeratinous carcinoma	1	2.4	41	97.6
Grade
G1	46	95.8	2	4.2	0.14
G2	7	77.8	2	22.2
G3	6	85.7	1	14.3
Depth of tumor invasion
<10 mm	1	2.3	42	97.7	0.02
≥10 mm	4	19.1	17	80.9
Fragmentation phenomenon
Absence	2	3.9	50	96.1	0.01
Presence	3	25.0	9	75.0
Tumor emboli in CD34-positive vessels
Absence	0	0	33	100.0	0.004
Presence	5	22.7	17	77.3
Tumor emboli in podoplanin-positive vessels
Absence	0	0	32	100.0	0.009
Presence	5	21.7	18	78.2
Depth of tumor invasion	4.6 ± 4.2		12.4 ± 6.4		0.01