Morphological Characteristics and Clinical Significance of Different Types of Tumor Vessels in Patients with Stages I-IIA of Squamous Cervical Cancer

Table 6

The presence of lymphatic vessels in lymphoid and polymorphic cell infiltrate depending on the clinical and the pathological cervical cancer characteristics and disease prognosis.

Indicators	Lymphatic vessels in the tumor stroma lymphoid and polymorphic cell infiltrates
	No, single		Multiple
	n	%	n	%
Age (years)
<35	10	55.6	8	44.4	0.26
35–44	8	53.3	7	46.7
≥45	24	75.0	8	25.0
Stages
IA	23	82.1	5	17.9	0.1
IB	17	53.1	15	46.9
IIA	2	40.0	3	60.0
Histology
Squamous cell keratinous carcinoma	32	74.4	11	25.6	0.04
Squamous cell nonkeratinous carcinoma	10	45.5	12	55.5
Grade
G1	42	85.7	7	14.3	0.57
G2	7	77.8	2	22.2
G3	5	71.4	2	28.6
Depth of tumor invasion
<10 mm	34	77.3	10	22.7	0.0004
≥10 mm	8	38.1	13	61.9
Fragmentation phenomenon
Absence	48	90.6	5	9.4	0.002
Presence	6	50.0	6	50.0
Tumor emboli in CD34-positive vessels
Absence	29	87.9	4	12.1	0.09
Presence	16	69.6	7	30.4
Tumor emboli in podoplanin-positive vessels
Absence	33	94.3	2	5.7	0.007
Presence	20	68.9	9	31.1
Recurrence
Absence	36	63.2	21	36.8	0.28
Presence	3	60.0	2	40.0