Clinical Study

Effectiveness of a Global Multidisciplinary Supportive and Educational Intervention in Thermal Resort on Anthropometric and Biological Parameters, and the Disease-Free Survival after Breast Cancer Treatment Completion (PACThe)

Table 3

Biological parameters at allocation.

Mean±σAll groups (n=113)BMI (kg/m2) value of BMI effect
≤25 (n = 57)25–30 (n = 38)>30 (n = 18)

Glucose (mmol/l)5.2±0.65.1 ± 0. 45.2 ± 0.65.6 ± 0.80.25
HDL-cholesterol (mmol/l)2.13±1.282.35 ± 1.351.98 ± 1.251.70 ± 0.970.0001
Transthyretin (g/l)0.26±0.040.26 ± 0.040.26 ± 0.040.26 ± 0.040.88
C-reactive protein (mg/l)2.5±3. 61.3 ± 1.23.2 ± 4.45.2 ± 4.90.000002
Insulin (mUI/l)6.5±6.24.7 ± 4.46.4 ± 4.412.1 ± 9.80.000013
IGF-1 (μg/l)96.4±49.395.8 ± 45.6103.5 ± 45.784.7 ± 62.60.23
Leptin (μg/l)5.7±4.73.5 ± 2.66.0 ± 3.012.1 ± 6.0<10−7
Adiponectin (mg/l)8.1±5.18.9 ± 5.37.6 ± 4.86.6 ± 4.40.072
Leptin/adiponectin ratio1.22±2.020.53 ± 0.511.26 ± 1.283.23 ± 3.86<10−7
Testosterone (nmol/l)0.82±0.360.79 ± 0.290.83 ± 0.420.87 ± 0.380.67
CA 15-3 (kU/l)18.1±18.720.1 ± 24.514.1 ± 9.019.7 ± 8.40.014

Plasma biological parameters are expressed in usual unit per liter. Comparison of outcomes per BMI group at allocation was tested with one-way analysis of variance (ANOVA). The test was two-sided, and the nominal level of significance was 5%.