Attenuated Total Reflection-Fourier Transform Infrared (ATR-FTIR) Spectroscopy Analysis of Saliva for Breast Cancer Diagnosis

Table 2

Clinical, hormonal, diagnostic, and therapy characteristics of breast cancer patients.

Variable	Patients (n = 10)
	N	%
Histological subtype
Invasive ductal carcinoma	6	60
In situ ductal carcinoma	3	30
Mucinous carcinoma	1	10
Histological grade
G2	5	50
G3	2	20
NR	3	30
Primary tumor
ptx	1	10
pTis	3	30
pT1	4	40
pT2	2	20
Regional lymph nodes
pNX	2	20
pN0	5	50
pN1	1	10
pN2	1	10
NR	1	10
Distant metastases
pM0	7	70
NR	3	30
TNM staging
0	2	20
I	1	10
II	2	20
NR	5	50
Status ER
Positive	8	80
NR	2	20
Status PR
Positive	8	80
NR	2	20
Status HER2
Positive	2	20
Negative	6	60
NR	2	20
p53
Positive	8	80
NR	2	20
Ki67
≤14%	5	50
>14%	3	30
NR	2	20
Molecular phenotype
Luminal A	4	40
Luminal B	4	40
NR	2	20
Therapy
Surgery (S)	1	10
S + radiotherapy (RT)	1	10
S + RT + hormone therapy (HT)	3	30
S + RT + HT + chemotherapy (CT)	5	50

G1, grade 1; G2, grade 2; G3, grade 3; NR, not reported; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; p53, tumor protein p53; ki67, antigen ki67.