Physical Properties of Nanoparticles That Result in Improved Cancer Targeting

Figure 4

Effect of contact angle on the internalization efficacy. Nanoparticles having a prolate ellipsoid morphology (major axis 0.35–2 nm, minor axis 0.2–2 nm) had the slowest internalization rate and the highest attachment rate in comparison to spheroidal morphology (radius 0.26–1.8 nm) and oblate ellipsoidal nanoparticles (major axis 0.35–2.5 nm, minor axis 0.2–2 nm) [37].