Somatic Mutation Profiling of Intrahepatic Cholangiocarcinoma: Comparison between Primary and Metastasis Tumor Tissues

Table 4

Immune cell type of mutated gene in primary ICC and metastatic ICC patient.

Source	Type	Gene
Primary	B cells memory	CD1C; CD79 B; CD79 A; BLK; CD22; CD79 B; CD22; CD79 A; BLK; CD79 B; and CD22
	B cells naive	BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; BRAF; and BRAF
	Dendritic cells activated	BIRC3; MAP3K13; CD1E; MAP3K13; MAP3K13; MAP3K13; NR4A3; BIRC3; and MAP3K13
	Dendritic cells resting	CD1A and CD1A
	Macrophages M1	SOCS1
	Mast cells activated	NTRK1; MYB; and NTRK1
	Monocytes	HCK; CD1D; and HCK
	Neutrophils	CEACAM3; CEACAM3; and CEACAM3
	NK cells activated	CCND2; CDK6; CCND2; CDK6; and CDK6
	Plasma cells	PAX7
	T cells CD4 memory resting	ITK; IL7R; and ITK
	T cells follicular helper	TSHR and PDCD1
	T cells regulatory (Tregs)	CD70
Metastasis	B cells memory	CD79 A
	Dendritic cells activated	MAP3K13
	Mast cells activated	MYB and NTRK1
	Monocytes	HCK
	T cells CD4 memory resting	IL7R