The Predictive Value of 2D Myocardial Strain for Epirubicin-Induced Cardiotoxicity

Table 4

Univariate analysis of echocardiographic predictors of cardiotoxicity at 12 months.

	All patients (n = 64)	C+ (n = 3)	C− (n = 61)	-value
Median LVEF T3	65% [54–76]	63% [54–68]	61% [54–76]	0.408
Median GLS T3	−19.5% [−24, −15]	−16% [−19, −15]	−20% [−24, −16.8]	0.022
Median GLS T3 variation	4.8% [0–28.5]	15.7% [9–28.5]	4.7% [4–23.5]	0.008

CTRCD+: patients who presented with cardiotoxicity at T12 consultation. CTRCD-: patients who did not present with cardiotoxicity during follow-up. T3: at three months. GLS: global longitudinal strain. LVEF: left ventricular ejection fraction.