Olaparib Outcomes in Patients with BRCA 1-2 Mutated, Platinum-Sensitive, Recurrent Ovarian Cancer in Croatia: A Retrospective Noninterventional Study

Table 3

Safety outcomes.

	Any grade		Grades 3-4
	n (%)	(95% CI)	n (%)	(95% CI)
Any toxicity	61 (88)	(78–95)	12 (17)	(9–28)
Hematologic toxicity	35 (51)	(38–63)	12 (17)	(9–28)
Anemia	29 (42)	(30–55)	9 (13)	(6–23)
Neutropenia	14 (20)	(12–32)	3 (4)	(1–12)
Elevation of creatinine	10 (14)	(7–25)	1 (1)	(0–8)
Thrombocytopenia	4 (6)	(2–14)	3 (4)	(1–12)
Nonhematologic toxicity	54 (78)	(67–87)	0 (0)	(0–5)
Fatigue	48 (70)	(57–80)	0 (0)	(0–5)
Nausea	31 (45)	(33–57)	0 (0)	(0–5)
Constipation	4 (6)	(2–14)	0 (0)	(0–5)
Vomit	3 (4)	(1–12)	0 (0)	(0–5)
Diarrhea	3 (4)	(1–12)	0 (0)	(0–5)
Artalgia	3 (4)	(1–12)	0 (0)	(0–5)
Abdominal pain	2 (3)	(0–10)	0 (0)	(0–5)