Comparison between Intensity-Modulated Radiotherapy and Three-Dimensional Conformal Radiotherapy for Their Effectiveness in Esophageal Cancer Treatment: A Retrospective Single Institution Study

Table 1

Characteristics of the EC patients grouped by the radiotherapy technique.

Characteristic	IMRT (n = 138)	3D-CRT (n = 293)	value
Gender			0.094
Male	128 (92.8%)	256 (87.4%)
Female	10 (7.2%)	37 (12.6%)
Age (years)			0.209
<55	36 (26.1%)	63 (21.5%)
55∼65	56 (40.6%)	107 (36.5%)
65∼75	34 (24.6%)	76 (26.0%)
≥75	12 (8.7%)	47 (16.0%)
Type of medical insurance			0.307
None	30 (21.7%)	83 (28.3%)
New rural cooperative medical insurance	27 (19.6%)	58 (19.8%)
Urban employee or resident insurance	81 (58.7%)	152 (51.9%)
Smoking status			0.078
No	26 (18.9%)	78 (26.6%)
Yes	112 (81.1%)	215 (73.4%)
Smoking intensity (cig/d)			0.331
1∼10	5 (4.5%)	22 (10.2%)
11∼20	25 (22.3%)	41 (19.1%)
21∼40	69 (61.6%)	128 (59.4%)
>40	13 (11.6%)	24 (11.3%)
Smoking duration (years)			0.331
<20	3 (2.7%)	13 (6.0%)
20∼40	72 (64.3%)	126 (58.6%)
≧40	37 (33.0%)	76 (35.4%)
Quit smoking			0.013
No	100 (89.3%)	168 (78.1%)
Yes	12 (10.7%)	47 (21.9%)
Drinking status			0.793
No	50 (36.2%)	110 (37.5%)
Yes	88 (63.8%)	183 (62.5%)
Alcohol consumption			0.314
Low risk	22 (25.0%)	48 (26.2%)
Medium risk	11 (12.5%)	23 (12.6%)
High risk	33 (37.5%)	50 (27.3%)
Very high risk	22 (25.0%)	62 (33.9%)
Drinking duration (years)			0.094
<20	16 (18.2%)	30 (16.4%)
20∼40	49 (55.7%)	100 (54.6%)
>40	23 (26.1%)	53 (29.0%)
Quit drinking			0.326
No	75 (85.2%)	147 (80.3%)
Yes	13 (14.8%)	36 (19.7%)
Weight loss (kg)			0.183
No	10 (7.2%)	29 (9.9%)
<5	76 (55.1%)	184 (62.8%)
≧5, <10	29 (21.0%)	40 (13.6%)
≧10, <15	13 (9.5%)	27 (9.2%)
≧15	10 (7.2%)	13 (4.5%)
Pathology			0.121
Squamous cell carcinoma	120 (87.0%)	229 (78.1%)
Adenocarcinoma	2 (1.4%)	16 (5.5%)
Adenosquamous carcinoma	1 (0.7%)	4 (1.4%)
Small-cell carcinoma	0 (0.0%)	4 (1.4%)
Unknown	15 (10.9%)	40 (13.6%)
Chemotherapy			0.0001
No	59 (42.8%)	183 (62.5%)
Yes	79 (57.2%)	110 (37.5%)
Concurrent chemotherapy			0.286
5-Fu + Platinum-based drugs	55 (70.5%)	68 (63.6%)
Cisplatin	8 (10.3%)	20 (18.7%)
Others	15 (19.2%)	19 (17.7%)
Radiation dose (Gy)			0.171
<60	55 (39.9%)	97 (33.1%)
≧60	83 (60.1%)	196 (66.9%)
Previous treatment			0.004
No	75 (54.3%)	201 (68.6%)
Yes	63 (45.7%)	92 (31.4%)
Previous treatment methods			0.001
Surgery	36 (57.1%)	67 (72.8%)
Chemotherapy	5 (7.9%)	16 (17.4%)
Radiation therapy	16 (25.5%)	8 (8.7%)
Chemoradiotherapy	6 (9.5%)	1 (1.1%)

EC, esophageal cancer; IMRT, intensity-modulated radiation therapy; 3D-CRT, three-dimensional conformal radiation therapy; kg, kilogram; Gy, gray unit.