The Value of Preoperative Alpha-L-Fucosidase Levels in Evaluation of Malignancy and Differential Diagnosis of Urothelial Neoplasms

Table 4

Multivariate analysis of preoperative variables prognostic for pure UC, UCSD, and SqCC.

Variables	UC versus papilloma and PUNLMP		Pure UC versus UCSD		Pure UC versus SqCC
	HR (95% CI)		HR (95% CI)		HR (95%CI)
Sex	1.080 (0.564∼2.070)	0.816	0.968 (0.220∼4.256)	0.965	0.192 (0.050∼0.740)	0.016
Hematuria	2.154 (1.237∼3.750)	0.007	4.761 (1.116∼20.303)	0.035	3.259 (0.880∼12.065)	0.077
Tumor size	4.374 (2.246∼8.517)	0.000	3.905 (0.769∼19.828)	0.100	1.475 (0.381∼5.706)	0.574
WBC	1.300 (0.744∼2.270)	0.357	1.584 (0.371∼6.765)	0.535	7.714 (1.504∼39.568)	0.014
LDH	1.525 (0.875∼2.658)	0.136	2.340 (0.537∼10.187)	0.257	2.020 (0.518∼7.879)	0.311
AFU level (>13.59 versus ≤ 13.59)	1.587 (0.913∼2.760)	0.102		n.d.		n.d.
AFU level (>11.50 versus ≤ 11.50)		n.d.	3.235 (0.792∼13.213)	0.102		n.d.
AFU level (>15.67 versus ≤ 15.67)		n.d.		n.d.	4.736 (0.573∼39.145)	0.149

Bold values are statistically significant (). HR: hazard ratio; 95% CI: 95% confidence interval; n.d.: not done.