Research Article

Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia

Table 2

Types of drug-related problems identified at the pediatric hematology/oncology ward of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, 25 June–25 October, 2018.

Types of DRPsCauses of DRPsNo. of DRPsTotal(%)

Unnecessary drug therapyDuplicate therapy12259.7
No medical indication at this time13

Needs additional therapyPreventive therapy497027.2
Untreated condition20
Synergistic therapy1

Ineffective drugMore effective drug available6114.3
Dosage form inappropriate5

Dosage too lowIneffective dose486023.3
Frequency inappropriate10
Duration inappropriate2

Adverse drug reactionUndesirable effect6145.5
Drug interaction1
Incorrect administration1
Dosage increase/decrease too fast6

Dosage too highDose too high284116.0
Needs additional monitoring3
Frequency too short7
Duration too long3

NonadherenceDoes not understand instructions63614.0
Cannot afford drug product1
Patient prefers not to take5
Patient forgets to take1
Drug product not available22
Cannot swallow/administer drug1